Modeling nucleic acids
نویسندگان
چکیده
منابع مشابه
Modeling nucleic acids.
Nucleic acids are an important class of biological macromolecules that carry out a variety of cellular roles. For many functions, naturally occurring DNA and RNA molecules need to fold into precise three-dimensional structures. Due to their self-assembling characteristics, nucleic acids have also been widely studied in the field of nanotechnology, and a diverse range of intricate three-dimensio...
متن کاملModeling large nucleic acids
During the past year, a variety of methods have been developed with which to investigate the structures of large nucleic acids. Modeling techniques ‘are assisting in the refinement of structures, particularly for large RNAs. Supercoiled DNA plasmids are being investigated using models that mimic the known elastic properties of the molecule. The level of detail in a particular modeling method mu...
متن کاملNucleic Acids: Qualitative Modeling
Knowledge about RNA three-dimensional structure is essential to RNA function comprehension and manipulation. Due to difficulties associated with physical RNA structure elucidation techniques, such as x-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy, it is not surprising that predictive methods are increasingly gaining popularity. Consequent to many genome sequencing proje...
متن کاملNucleic Acids
The first isolation of what we now refer to as DNA was accomplished by Johann Friedrich Miescher circa 1870. He reported finding a weakly acidic substance of unknown function in the nuclei of human white blood cells, and named this material "nuclein". A few years later, Miescher separated nuclein into protein and nucleic acid components. In the 1920's nucleic acids were found to be major compon...
متن کاملNucleic acids.
In: Dyer A, Hudson HG and Williams PA (eds) Ion Exchange Processes: Advances and Applications, p. 39. Cambridge, UK: The Royal Society of Chemistry. Lehto J and Harjula R (1997) Selective separation of radionuclides from nuclear waste solutions with inorganic ion exchangers, React Funct Polym (in press). Navratil JD (1989) Ion exchange technology in spent fuel reprocessing. Journal of Nuclear S...
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2012
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2012.03.012